Session Type: General Session

Dudrick Research Symposium: Lipids in Clinical Medicine: Is It Time for Fat to be Therapeutic? (M10)

General Session

Date & Time:

March 24, 2025

8:00 AM – 9:30 AM ET

Format:

In Person & Virtual

CE Credits:

1.5 Hours

UAN: JA0002345-0000-25-043-L99-P

Course level:

Advanced

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session objectives:

What You'll Learn

Since the days of the Seven Countries Study led by Dr. Ancel Keys, which demonstrated the link between dietary saturation fat intake and coronary heart disease, our focus in health care has been on the detrimental health effects of fat. However, recent developments have begun to change this negative connotation. The 2025 Dudrick Research Symposium will highlight  cutting-edge research that is being performed in the realm of fatty acids, including the benefit of fish oil/omega-3 fatty acids, the clinical utility of specialized pro-resolving mediators, and the benefits and future potential for use of modified fatty acids in parenteral nutrition (PN) related complications.

 

LEARNING OBJECTIVES

  • Summarize the impact of modified fatty acids in the prevention and treatment of PN related complications such as IFALD.
  • Discuss the benefit of fish oil in general health and nutrition support.
  • Outline the physiology of specialized pro-resolving mediators and their clinical utility.

Topics & Presenters

Benefit of Modified Fatty Acids

Mark Puder
MD, PhD

Professor of Surgery

Harvard Medical School

Attending Surgeon

Department of Surgery, Boston Children's Hospital

Boston, MA

Is it Time for Bioactive Lipids, EPA and DHA to Take Center Stage in Nutritional Pharmacology Again?

Robert Martindale
MD, PhD, FASPEN

Professor of Surgery

Division of Gastrointestinal and General Surgery, Oregon Health & Science University

Medical Director

Hospital Nutrition Services, Oregon Health & Science University

Portland, OR

Insights Into the Biology of Specialized Pro-Resolving Mediators

Jesmond Dalli
PhD

Professor of Molecular Pharmacology

Barts and The London School of Medicine and Dentistry, Queen Mary University of London

Lipid Mediator Unit Director

William Harvey Research Institute, Queen Mary University of London

London, England United Kingdom

Moderators:

Manpreet S. Mundi

MD

Professor of Medicine

Division of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic

Rochester, MN

Keynote Address: The Next 50 Years – Challenges and Opportunities in Clinical Nutrition (SU10)

General Session

Date & Time:

March 23, 2025

7:45 AM – 9:15 AM ET

Format:

In Person & Virtual

CE Credits:

1.25 Hours

UAN: JA0002345-0000-25-024-L99-P

Course level:

Intermediate

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session objectives:

What You'll Learn

It is time to think outside of the box as we contemplate future directions and priorities in clinical nutrition. The necessity of challenging dogma and asking questions when things do not make sense is an important area of emphasis. Innovation skills prioritize new ways of looking at challenging problems and bringing new perspectives and creative solutions to the table.  

Do not miss this keynote session where you will have an opportunity to learn from three exceptional presenters who will share approaches that are integral to successful innovation as we look ahead to the next 50 years.  

  • Describe fundamental innovation skills.  
  • Identify at least three breakthroughs in clinical nutrition that resulted from thinking outside the box. 
  • Describe the key challenges and opportunities that we face in clinical nutrition. 

Topics & Presenters

The Importance of Thinking Outside the Box

Gordon-Jensen
Gordon Lee Jensen
MD, PhD, FASPEN

Senior Associate Dean for Research Emeritus

Larner College of Medicine at the University of Vermont

Professor of Medicine and Nutrition Emeritus

Larner College of Medicine at the University of Vermont

Burlington, VT

Artificial Intelligence in Health and Nutrition

Ryan Hurt
Ryan T. Hurt
MD, PhD, FASPEN

Professor of Medicine

Mayo Clinic College of Medicine

Rochester, MN

Artificial Intelligence in Health and Nutrition

Anju Gupta
PhD

Vice President, Data Science AI/ML

Northwestern Mutual

St. Louis, MO

Rhoads Lecture and Awards Ceremony: Advancements in Pediatric Parenteral Lipid Nutrition and Impact on Hepatic Function Using the Neonatal Pig Model (T10)

General Session

Doug Burrin
Douglas G. Burrin
PhD

In the prestigious Rhoads Research Lecture, Dr. Burrin will highlight his past and current research discoveries in pediatric nutrition. He will also highlight the importance of the neonatal pig as a pre-clinical model in addressing important questions and challenges faced by clinicians in the nutritional support of hospitalized infants.

Read Biography

Dr. Douglas G. Burrin obtained degrees in animal science at Purdue University and the University of Nebraska. He completed a postdoctoral fellowship at the USDA Agricultural Research Service (ARS) Children’s Nutrition Research Center (CNRC) in Houston where he is currently appointed as a Research Physiologist with USDA-ARS and Professor of Pediatrics at Baylor College of Medicine (BCM).

Dr. Burrin is recognized for his knowledge and expertise in the fields of human nutrition, metabolism, and gastroenterology. Dr. Burrin has been a leader in the use of the pig as a translational animal model of human pediatric nutrition and gastroenterology. His research has highlighted the importance of enteral nutrition and the function of key gut hormones, such glucagon-like peptide 2 and fibroblast growth factor 19, in the pathogenesis of pediatric GI and liver disease. He has also made important contributions in understanding how parenteral nutrition and lipid emulsions impact intestinal adaptation and liver disease.

He has received national awards for his research, including the Mead Johnson Award from the American Society for Nutrition, the Growth and Development Award from the American Society for Animal Science, the ARS Senior Scientist of the Year, and the Bruce Bistrian Mentorship Award from ASPEN. His leadership in mentoring has been recognized by the Excellence in Research Mentorship Award from the Department of Pediatrics at BCM. He has mentored 60 postdoctoral fellows and graduate students resulting in 70 peer-reviewed articles.

He currently serves on the editorial board of the American Journal of Physiology-GI & Liver Section. Dr. Burrin is also a Director of the fellowship research training in the Division of Pediatric Gastroenterology, Hepatology, and Nutrition at Baylor College of Medicine. He also serves in the leadership of the NIDDK-funded Texas Medical Center Digestive Disease Center and as Director, Pilot and Feasibility Program. He has served on the ASPEN Task Force on Intravenous Lipid Emulsions and is a past member of the ASPEN Rhoads Research Foundation Grant Review Committee and Board Member.

Date & Time:

March 25, 2025

8:00 AM – 9:15 AM ET

Format:

In Person & Virtual

CE Credits:

1.0 Hours

UAN: JA0002345-0000-25-057-L99-P

Course level:

Advanced

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session objectives:

What You'll Learn

  • Identify the unique features of neonatal pigs as an animal model for human infants and clinical nutrition.
  • Summarize the advancements in parenteral lipid metabolism and its impact on hepatic function using the neonatal pig model.

Topics & Presenters

Advancements in Pediatric Parenteral Lipid Nutrition and Impact on Hepatic Function Using the Neonatal Pig Model

Douglas G. Burrin
PhD

Distinguished Senior Research Scientist

U.S. Department of Agriculture - Agricultural Research Service, Children’s Nutrition Research Center

Professor of Pediatrics

Baylor College of Medicine

Houston, TX

President’s Address: A Gut Feeling – The Story of Short Bowel Syndrome (SA10)

General Session

Ajay Jain
Ajay Jain
MD, DNB, MHA

Join us for an exciting start to ASPEN25 with Ajay Jain, MD, DNB, MHA, ASPEN’s 48th president! Dr. Jain will lead us through a presentation on the story of short bowel syndrome during his presidential address.  

Read Biography

Dr. Jain is a professor of pediatrics, pharmacology, and physiology at Saint Louis University School of Medicine in Saint Louis, Missouri. He also serves as chief of the Division of Pediatric Gastroenterology, Hepatology and Nutrition; director of Pediatric Liver Transplantation; and director of the Healthy First Program at SSM Health Cardinal Glennon Children’s Hospital. 

His interest in nutrition began in medical school when he cared for babies needing parenteral nutrition (PN). While PN sustained them, many had liver injuries that progressed as they stayed on PN and, thus, needed liver transplants. This motivated Dr. Jain to focus on novel strategies to mitigate the injuries and side effects of PN on patients. 

Dr. Jain has received research funding from the National Institutes of Health and various foundations. Dr. Jain’s seminal contributions include groundbreaking work in parenteral nutrition-associated multisystem injury, interrogating pathways, and leading the development of novel systems to study pathogenesis, diagnosis, and therapeutic approaches for appropriate nutrition delivery and rehabilitation. He is also credited with developing unbiased discovery platforms and excellence in diagnostic and therapeutic testing of pediatric liver diseases and pediatric obesity. 

An active and engaged ASPEN member, Dr. Jain has chaired the Research Committee and served on the Stanley Dudrick Research Scholar Award Committee, the Physician Engagement Committee, the Conference Program Committee, and the board of the ASPEN Rhoads Research Foundation. Dr. Jain has been on the ASPEN Board of Directors since 2020.  

Date & Time:

March 22, 2025

1:00 PM – 2:15 PM ET

Format:

In Person & Virtual

CE Credits:

1.0 Hours

UAN: JA0002345-0000-25-018-L99-P

Course level:

Intermediate

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session objectives:

What You'll Learn

  • Describe the evolution of our understanding and definition of short bowel syndrome
  • Summarize the multifactorial etiology resulting in short bowel syndrome
  • Examine the current literature on mechanistic drivers of injury in short bowel syndrome
  • Explain gut-systemic cross signaling
  • Interpret and critique novel diagnostics and therapeutic strategies

Topics & Presenters

A Gut Feeling – The Story of Short Bowel Syndrome

Ajay Jain
MD, DNB, MHA

Chief of the Division of Pediatric Gastroenterology, Hepatology and Nutrition; Director of Pediatric Liver Transplantation

SSM Health Cardinal Glennon Children's Hospital

Professor of Pediatrics, Pharmacology, and Physiology

Saint Louis University School of Medicine

St. Louis, MO

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